論文（総説）紹介

T.R. Cech

  1. Gray J.T., Hicke B., Celander D., Price C., Cech T.R., Biochemical characterization of telomere binding proteins from Oxytricha nova. , Abst. IV Int. Conf. Ciliate Mol. Biol., , , 33, 1991
  2. Pyle A.M., Cech T.R., Ribozyme recognition of RNA by tertiary interactions with specific ribose 2'-OH groups. , Nature, 350, 6319, 628-631, 1991
  3. Zahler A.M., Williamson J.R., Cech T.R., Prescott D.M. , G-quartet structure in a telomere sequence inhibits telomerase. , Abst. IV Int. Conf. Ciliate Mol. Biol., , , 116, 1991
  4. Flor P.J., Flanegan J.B., Cech T.R., A conserved base pair within helix P4 of the Tetrahymena ribozyme helps to form the tertiary structure required for self-splicing. , EMBO J., 8, 11, 3391-3399, 1989
  5. Grosshans C.A., Cech T.R., Metal ion requirements for sequence-specific endoribonuclease activity of the Tetrahymena ribozyme. , Biochemistry, 28, , 6888-6894, 1989
  6. McSwiggen J.A., Cech T.R., Stereochemistry of RNA cleavage by the Tetrahymena ribozyme and evidence that the chemical step is not rate-limiting., Science, 244, , 679-683, 1989
  7. Murphy F.L., Cech T.R., Alteration of substrate-specificity for the endoribonucleolytic cleavage of RNA by the Tetrahymena robozyme., Proc. Natl. Acad. Sci. USA, 86, 23, 9218-9222, 1989
  8. Price C.M., Cech T.R., Properties of the telomeric DNA-binding protein from Oxytricha nova., Biochemistry, 28, 2, 769-774, 1989
  9. Raghuraman M.K., Cech T.R., Assembly and self-association of Oxytricha telomeric nucleoprotein complexes. , Cell, 59, , 719-728, 1989
  10. Raghuraman M.K., Dunn C.J., Hicke B.J., Cech T.R., Oxytricha telomeric nucleoprotein complexes reconstituted with synthetic DNA., Nucl. Acids Res., 17, 11, 4235-4253, 1989
  11. Williamson J.R., Raghuraman M.K., Cech T.R., Monovalent cation-induced structure of telomeric DNA: the G-quartet model., Cell, 59, , 871-880, 1989
  12. Woodson S.A., Cech T.R., Reverse self-splicing of the Tetrahymena group I intron: implication for the directionality of splicing and for intron transposition., Cell, 57, , 335-345, 1989
  13. Yarus M., Levine J., Morin G.B., Cech T.R., A Tetrahymena intron nucleotide connected to the GTP/arginine site. , Nucl. Acids Res., 17, 17, 6969-6981, 1989
  14. Barfod E.T., Cech T.R., Deletion of nonconserved helices near the 3' end of the rRNA intron of Tetrahymena thermophila alters self-splicing but not core catalytic activity., Genes Dev., 2, , 652-663, 1988
  15. Been M.D., Cech T.R., RNA as an RNA polymerase: net elongation of an RNA primer catalyzed by the Tetrahymena ribozyme., Science, 239, , 1412-1416, 1988
  16. Morin G.B., Cech T.R., Mitochondrial telomeres: surprising diversity of repeated telomeric DNA sequences among six species of Tetrahymena., Cell, 52, , 367-374, 1988
  17. Morin G.B., Cech T.R., Telomeric repeats of Tetrahymena malaccensis mitochondrial DNA: a multimodal distribution that fluctuates erratically during growth., Mol. Cell. Biol., 8, 10, 4450-4458, 1988
  18. Morin G.B., Cech T.R., Phylogenetic relationships and altered genome structures among Tetrahymena mitochondrial DNAs., Nucl. Acids Res., 16, 1, 327-346, 1988
  19. Price J.V., Cech T.R., Determinants of the 3' splice site for self-splicing of the Tetrahymena pre-rRNA., Genes Dev., 2, , 1439-1447, 1988
  20. Zaug A.J., Grosshans C.A., Cech T.R., Sequence-specific endoribonuclease activity of the Tetrahymena ribozyme: enhanced cleavage of certain oligonucleotide substrates that form mismatched ribozyme-substrate complexes., Biochemistry, 27, 25, 8924-8931, 1988
  21. Been M.D., Barfod E.T., Burke J.M., Price J.V., Tanner N.K., Zaug A.J., Cech T.R., Structure involved in Tetrahymena rRNA self-splicing and RNA enzyme activity., Cold Spring Harbor Symp. ??, 52, , 147-157, 1987
  22. Kim S.-H., Cech T.R., Three-dimensional model of the active site of the self-splicing rRNA precursor of Tetrahymena., Proc. Natl. Acad. Sci. USA, 84, , 8788-8792, 1987
  23. Price C.M., Cech T.R., Telomeric DNA-protein interactions of Oxytricha macronuclear DNA., Genes Dev., 1, , 783-793, 1987
  24. Price J.V., Engberg J., Cech T.R., 5' exon requirement for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA and identification of a cryptic 5' splice site in the 3' exon., J. Mol. Biol., 196, , 49-60, 1987
  25. Bass B.L., Cech T.R., Ribozyme inhibitors: deoxyguanosine and dideoxyguanosine are competitive inhibitors of self-splicing of the Tetrahymena ribosomal ribonucleic acid precursor., Biochemistry, 25, , 4473-4477, 1986
  26. Burke J.M., Irvine K.D., Kaneko K.J., Kerker B.J., Oettgen A.B., Tierney W.M., Williamson C.L., Zaug A.J., Cech T.R., Role of conserved sequence elements 9L and 2 in self-splicing of the Tetrahymena ribosomal RNA precursor., Cell, 45, , 167-176, 1986
  27. Garriga G., Lambowitz A.M., Inoue T., Cech T.R., Mechanism of recognition of the 5' splice site in self-splicing group I introns., Nature, 322, 6074, 86-89, 1986
  28. Inoue T., Sullivan F.X., Cech T.R., New reactions of the ribosomal RNA precursor of Tetrahymena and the mechanism of self-splicing., J. Mol. Biol., 189, , 143-165, 1986
  29. Morin G.B., Cech T.R., The telomeres of the linear mitochondrial DNA of Tetrahymena thermophila consist of 53 bp tandem repeats., Cell, 46, , 873-883, 1986
  30. Zaug A.J., Been M.D., Cech T.R., The Tetrahymena ribozyme acts like an RNA restriction endonuclease., Nature, 324, 6096, 429-433, 1986
  31. Zaug A.J., Cech T.R., The Tetrahymena intervening sequence ribonucleic acid enzyme is a phosphotransferase and an acid phosphatase., Biochemistry, 25, , 4478-4482, 1986
  32. Zaug A.J., Cech T.R., The intervening sequence RNA of Tetrahymena is an enzyme., Science, 231, , 470-475, 1986
  33. Been M.D., Cech T.R., Sites of circularization of the Tetrahymena rRNA IVS are determined by sequence and influenced by position and secondary structure., Nucl. Acids Res., 13, 23, 8389-8408, 1985
  34. Inoue T., Cech T.R., Secondary structure of the circular form of the Tetrahymena rRNA intervening sequence: A technique for RNA structure analysis using chemical probes and reverse transcriptase., Proc. Natl. Acad. Sci. USA , 82, , 648-652, 1985
  35. Inoue T., Sullivan F.X., Cech T.R., Intermolecular exon ligation of the rRNA precursor of Tetrahymena: oligonucleotides can function as 5' exons., Cell, 43, 1, 431-437, 1985
  36. Price J.V., Cech T.R., Coupling of Tetrahymena ribosomal RNA splicing to b-galactosidase expression in Escherichia coli. , Science, 228, , 719-722, 1985
  37. Price J.V., Kieft G.L., Kent J.R., Sievers E.L., Cech T.R., Sequence requirements for self-splicing of the Tetrahymena thermophila pre-ribosomal RNA., Nucl. Acids Res., 13, 6, 1871-1889, 1985
  38. Sullivan F.X., Cech T.R., Reversibility of cyclization of the Tetrahymena rRNA intervening sequence: implication for the mechanism of splice site choice., Cell, 42, , 639-648, 1985
  39. Tanner N.K., Cech T.R., Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by intercalating dyes., Nucl. Acids Res., 13, 21, 7741-7758, 1985
  40. Tanner N.K., Cech T.R., Self-catalyzed cyclization of the intervening sequence RNA of Tetrahymena: inhibition by methidiumpropyl-EDTA and localization of the major dye binding sites., Nucl. Acids Res., 13, 21, 7759-7779, 1985
  41. Zaug A.J., Kent J.R., Cech T.R., Reactions of the intervening sequence of the Tetrahymena ribosomal ribonucleic acid precursor: pH dependence of cyclization and site-specific hydrolysis., Biochemistry, 24, , 6211-6218, 1985
  42. Bass B.L., Cech T.R., Specific interaction between the self-splicing RNA of Tetrahymena and its guanosine substrate: implications for biological catalysis by RNA., Nature, 308, 5962, 820-826, 1984
  43. Gottschling D.E., Cech T.R., Chromatin structure of the molecular ends of Oxytricha macronuclear DNA: phased nucleosomes and a telomeric complex., Cell, 38, , 501-510, 1984
  44. Palen T.E., Cech T.R., Chromatin structure at the replication origins and transcription-initiation regions of the ribosomal RNA genes of Tetrahymena., Cell, 36, , 933-942, 1984
  45. Zaug A.J., Kent J.R., Cech T.R., A labile phosphodiester bond at the ligation junction in a circular intervening sequence RNA., Science, 224, , 574-578, 1984
  46. Brehm S.L., Cech T.R., Fate of an intervening sequence ribonucleic acid: excision and cyclization of the Tetrahymena ribosomal ribonucleic acid intervening sequence in vivo., Biochemistry, 22, 10, 2390-2397, 1983
  47. Cech T.R., Tanner N.K., Tinoco I.Jr., Weir B.R., Zuker M., Perlman P.S., Secondary structure of the Tetrahymena ribosomal RNA intervening sequence: Structural homology with fungal mitochondrial intervening sequences., Proc. Natl. Acad. Sci. USA, 80, , 3903-3907, 1983
  48. Kruger K., Grabowski P.J., Zaug A.J., Sands J., Gottschling D.E., Cech T.R., Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of Tetrahymena. , Cell, 31, , 147-157, 1982
  49. Tanner N.K., Cech T.R., Guanosine binding required for cyclization of the self splicing intervening sequence ribonucleic acid from Tetrahymena thermophila., Biochem, 26, 12, 3330-3340,